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. Author manuscript; available in PMC: 2026 Feb 18.
Published in final edited form as: IEEE Trans Med Imaging. 2026 Mar;45(3):1115–1126. doi: 10.1109/TMI.2025.3618247

TABLE V.

Adaptability of the LeqMod to different denoising baselines.

GAN SwinUNETR
NRMSE (↓) TLG bias (%) (o) NRMSE (↓) TLG bias (%) (o)
w/o w w/o w w/o w w/o w
Quadra 1% 0.273 0.266 −5.115 −4.444 0.294 0.284 −7.395 −5.304
2% 0.252 0.234 −4.092 −3.376 0.240 0.231 −5.617 −3.889
5% 0.196 0.194 −2.592 −2.328 0.207 0.216 −4.244 −2.980
10% 0.178 0.169 −1.787 −1.583 0.184 0.180 −3.312 −2.133
25% 0.146 0.131 −1.035 −0.879 0.173 0.137 −2.193 −1.163
50% 0.100 0.094 −0.699 −0.610 0.140 0.114 −2.095 −0.964
uExplorer 1% 0.551 0.536 −13.231 −9.671 0.574 0.555 −15.354 −13.586
2% 0.439 0.432 −8.601 −6.696 0.453 0.440 −11.286 −8.921
5% 0.354 0.353 −4.869 −4.163 0.371 0.349 −7.069 −5.080
10% 0.284 0.274 −3.285 −3.092 0.303 0.294 −5.371 −3.672
25% 0.213 0.224 −1.800 −1.679 0.231 0.226 −3.721 −2.249
50% 0.153 0.142 −1.016 −1.028 0.182 0.165 −2.805 −1.351
mCT 5% 0.538 0.527 −8.466 −7.428 0.531 0.524 −8.485 −7.507
10% 0.523 0.449 −5.828 −5.056 0.459 0.430 −6.070 −4.990
20% 0.344 0.339 −3.604 −3.037 0.361 0.348 −4.187 −3.712

P<0.05 based on the Wilcoxon signed-rank test between the w/o and w LeqMod groups.

(↓) and (o) represent expecting lower and zero-approaching values, respectively.