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Offspring from multiple matingsa
| Genotype | No. of pups
|
Total no. of litters | Avg litter size (SD) | ||
|---|---|---|---|---|---|
| Female | Male | Total | |||
| +/+ × +/+ | 53 | 66 | 119 | 18 | 6.5 (±2.3) |
| −/− × −/− | 82 | 88 | 170 | 23 | 7.4 (±2.5) |
Five pairs of wild-type (+/+) and mutant (−/−) mice were housed separately and allowed to mate for 4 months. Pups were separated from the parents after weaning.
