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Defects in the thymus from Akt1−/− Akt3+/− mice. (A) Thymi from P3 Akt1+/− Akt3+/− and Akt1−/− Akt3+/− littermates. (B to E) HE staining of the thymus from panel A. Panels B and C are lower-magnification images of panels D and E. Arrowheads in panel E indicate the Hassall's corpuscle-like structures in the Akt1−/− Akt3+/− mice which are not found in wild-type mouse thymus. Cap, capillary blood vessel. Magnification for panels B and C, ×40; for panels D and E, ×400.
