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Blood levels of select organic acids
| Organic acid | Mean blood level ± SEMa
|
|
|---|---|---|
| Control (n = 5) | Mck-cre; Aifflox/Y (n = 5) | |
| Lactate (mmol/liter) | 2.3 ± 0.3 | 5.5 ± 0.5 |
| Pyruvate (mmol/liter) | 0.12 ± 0.01 | 0.15 ± 0.01 |
| Lactate/pyruvate ratio | 18.7 ± 2.4 | 37.2 ± 4.7 |
Plasma was collected from 13-week-old littermate mice and analyzed for the indicated metabolites. Lactate, P < 0.001; pyruvate, P < 0.02; L/P, P < 0.005.
