TABLE 2.
Molecular masses of wild-type and mutant mPDFs
| Sample | Species | Radius (nm) | Polydispersity (%) | Molecular massa
|
|
|---|---|---|---|---|---|
| kDa | % | ||||
| Wild type | Multimer | 4.3 | 0.0 | 100 | 85.4 |
| Soluble aggregate | 20.4 | 11.4 | 3,907 | 13.4 | |
| ID | Multimer | 4.3 | 0.0 | 100 | 85.3 |
| Soluble aggregate | 17.7 | 19.9 | 2,808 | 12.3 | |
| TD | Multimer | 3.9 | 15.4 | 82 | 95.3 |
| Soluble aggregate | 23.1 | 17.3 | 5,239 | 4.7 | |
a
Molecular masses were determined by dynamic light-scattering studies, as mentioned in the text. All entries in the table are the means of values derived from a minimum of 20 independent measurements.