Table 5.
Association of the CTI with dyslipidemia incidence across physical activity levels.
| Physical activity | Variable | Number of events, n | Model 1 | Model 2 | Model 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | p | HR | 95% CI | p | HR | 95% CI | p | |||
| Light | CTI (per 1-unit) | 634 | 1.11 | 1.02-1.20 | 0.03 | 1.10 | 1.01-1.19 | 0.04 | 1.11 | 1.02-1.18 | 0.04 |
| Q1 (Ref) | 122 | ||||||||||
| Q2 | 141 | 1.03 | 0.87-1.22 | 0.72 | 1.02 | 0.86-1.21 | 0.76 | 1.03 | 0.85-1.22 | 0.77 | |
| Q3 | 170 | 1.07 | 0.91-1.27 | 0.33 | 1.06 | 0.90-1.26 | 0.36 | 1.04 | 0.87-1.23 | 0.36 | |
| Q4 | 201 | 1.25 | 1.05-1.49 | 0.02 | 1.23 | 1.04-1.47 | 0.03 | 1.21 | 1.02-1.44 | 0.03 | |
| P for trend | 0.02 | 0.03 | 0.03 | ||||||||
| Moderate | CTI (per 1-unit) | 982 | 1.12 | 1.03-1.21 | 0.01 | 1.11 | 1.02-1.20 | 0.02 | 1.11 | 1.02-1.17 | 0.02 |
| Q1 (Ref) | 163 | ||||||||||
| Q2 | 218 | 1.01 | 0.86-1.18 | 0.90 | 1.01 | 0.86-1.18 | 0.91 | 1.01 | 0.84-1.17 | 0.93 | |
| Q3 | 290 | 1.09 | 0.93-1.27 | 0.25 | 1.08 | 0.92-1.26 | 0.28 | 1.06 | 0.92-1.24 | 0.31 | |
| Q4 | 311 | 1.28 | 1.09-1.50 | 0.01 | 1.26 | 1.07-1.49 | 0.01 | 1.24 | 1.05-1.46 | 0.02 | |
| P for trend | 0.01 | 0.02 | 0.02 | ||||||||
| Vigorous | CTI (per 1-unit) | 395 | 1.30 | 1.08-1.56 | 0.01 | 1.29 | 1.07-1.55 | 0.01 | 1.26 | 1.05-1.53 | 0.02 |
| Q1 (Ref) | 95 | ||||||||||
| Q2 | 89 | 1.18 | 0.84-1.65 | 0.33 | 1.16 | 0.83-1.62 | 0.35 | 1.14 | 0.81-1.62 | 0.34 | |
| Q3 | 82 | 1.25 | 0.90-1.74 | 0.15 | 1.23 | 0.88-1.72 | 0.18 | 1.21 | 0.86-1.72 | 0.20 | |
| Q4 | 129 | 1.49 | 1.11-2.01 | 0.01 | 1.47 | 1.09-1.98 | 0.02 | 1.44 | 1.07-1.94 | 0.02 | |
| P for trend | 0.01 | 0.02 | 0.02 | ||||||||
HR = hazard ratio; CI = confidence interval. Q1 denotes the lowest quartile, which served as the reference category. Model 1 included no covariate adjustment; Model 2 was adjusted for demographic and lifestyle characteristics (sex, age, residence, marital status, education, smoking, and alcohol consumption); and Model 3 additionally accounted for comorbid conditions such as chronic diseases, arthritis, liver disease, asthma, kidney disease, and gastrointestinal disorders, as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates. The p for trend was estimated by modeling the median value of each quartile as a continuous variable in the Cox regression model. Statistical significance was defined as a two-sided p < 0.05.