Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
HPLC analysis of in vivo products. (A) HPLC patterns of compounds produced by S. lividans TK21 expressing P-450mel alone (pNF3), rppA alone (pNF2), and P-450mel and rppA (pNF1). As a negative control, the culture broth of S. lividans harboring the vector pIJ6021 was also analyzed. Both THN and flaviolin were identified by their comigration with authentic samples. (B) HPLC patterns of compounds produced by S. griseus wild-type (IFO13350), ΔP-450mel, and ΔrppA strains.
