TABLE 4.
Virulence properties in BALB/c mice of serovar Typhimurium dam mutants cured of prophages or with a defect in excision
Strain 1a | Strain 2a | Competition indexb
|
|
---|---|---|---|
Liver | Spleen | ||
dam | Wild type | 0.0012 ± 0.001 | 0.0009 ± 0.0002 |
dam Δ[Gifsy-1, Gifsy-2, SopEΦ, ST64B] | dam | 0.059 ± 0.013 | 0.027 ± 0.0003 |
dam Δ[Gifsy-1, Gifsy-2, SopEΦ, ST64B] sodC1+gtgE+ | dam | 0.97 ± 0.15 | 1.09 ± 0.54 |
dam [ST64B Δxis] | dam | 1.79 ± 0.48 | 1.17 ± 0.46 |
All these strains are isogenic to wild-type strain SL1344 (see Table 1 for details).
Values were calculated upon intraperitoneal challenge of three BALB/C mice per mixed infection. Organ homogenates were prepared at 48 to 72 hours postinfection.