Figure 2.
Same germinal center in spleen as in figure 1. Apoptotic cells (arrows) stain dark brown for active caspase 3. Immunohistochemistry, hematoxylin counterstain, Bar = 80 μm. Spleen from a PCV2-inoculated sPCV mouse 28 days PI. Large numbers of apoptotic cells (arrows) in sinusoids and germinal centers stain dark brown with TUNEL. In-situ hybridization, hematoxylin counterstain, Bar = 100 μm