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Translational opportunities from epigenetic alterations in cervical cancer
| Early detection | Identification of a set of hypermethylated genes from cytological smears |
| Prognostic/predictive | Determination of global methylation or histone modifications in tumor or peripheral blood cells Determination of hypermethylated gene promoters from serum/plasma DNA |
| Therapy | DNA methylation inhibitors and/or HDACs inhibitors alone or as chemo- or radio-sensitizers |
