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Effect of tolafentrine on PDGF-directed PASMCs migration. Tolafentrine at different concentrations (0.05, 0.1, and 0.3 μM) inhibited PDGF-BB (25 ng/ml)-induced MCT-treated rat PASMCs migration. The number of migrated cells was counted in 5 random areas per membrane. The results are based on three independent experiments. All values are given as mean ± SEM. *, p < 0.05 versus PDGF-BB stimulated PASMCs.
