Table 4.
Influence of platelet concentration on the normal values of thrombin generation parameters assessed by Thrombogram-Thrombinoscope in the presence of 1/2000 final dilution of recombiplastin corresponding to estimated TF concentration of 3 pM. (n = 7; means ± sd, *p < 0,05 versus the respective value in the presence of platelet counts 10 × 109/l.
| Platelet concentration (× 109/l) | lag-time (min) | Tmax (min) | Cmax (nM) | ETP (nM × min) |
| 400 | 5 ± 0,5 | 11 ± 2,7 | 161 ± 38 | 1633 ± 81 |
| 150 | 5,5 ± 0,5 | 11 ± 0,2 | 98 ± 40 | 1316 ± 255* |
| 100 | 5,8 ± 0,7* | 13 ± 0,9 | 72 ± 38 | 1135 ± 300 |
| 50 | 8 ± 3,3 | 12 ± 0,2* | 63 ± 14* | 1095 ± 301 |
| 10 | 8 ± 3 | 19 ± 2 | 43 ± 16 | 894 ± 100 |