Skip to main content
. 2026 Jan 22;16:1701694. doi: 10.3389/fphar.2025.1701694

FIGURE 2.

Bar and line graphs compare metabolic parameters in three groups: SD, PCOS, and PCOS+SZ-A. Panel A shows similar fasting blood glucose levels. Panel B indicates increased fasting insulin in PCOS with a decrease in PCOS+SZ-A. Panel C shows higher HOMA-IR in PCOS, reduced in PCOS+SZ-A. Panel D presents glucose tolerance curves and AUC indicating higher levels in PCOS. Panel E displays insulin tolerance test curves with comparable AUC across groups. Significant differences are marked with asterisks and hashtags.

Effects of SZ-A on glucose tolerance and insulin sensitivity in PCOS rats. After 12 h of fasting, Blood glucose levels (A) and insulin (B) were measured in SD, PCOS, and PCOS+SZ-A groups of rats (n = 6). The steady-state model evaluation of insulin resistance (HOMA-IR) index (C). Oral glucose tolerance tests (OGTTs) (D) and insulin tolerance tests (ITTs) (E) were performed on three groups of rats. Calculate the area under the curve (AUC) corresponding to blood glucose levels in each group. Values are shown as the mean ± SEM (n = 6 rats).*represents significance compared to the SD group (*p < 0.05), # represents significance compared to the PCOS group (#p < 0.05). One-way ANOVA followed by Turkey’s test was used for all results.