Table 2.
Spearman’s rank correlation coefficients between QSM and neuropathologic measurements
| QSM | ||||
|---|---|---|---|---|
| Ventromedial | Dorsomedial | Ventrolateral | Dorsolateral | |
| Pigmented neuron density | − 0.014 (P = 0.92) | − 0.35 (P = 0.007) | − 0.26 (P = 0.050) | − 0.26 (P = 0.053) |
| Non-pigmented neuron density | 0.085 (P = 0.53) | 0.055 (P = 0.68) | 0.066 (P = 0.63) | 0.026 (P = 0.85) |
| Tau %AO | 0.45 (P = 0.002) | 0.26 (P = 0.087) | 0.23 (P = 0.13) | 0.18 (P = 0.23) |
| Iron %AO | 0.41 (P = 0.002) | 0.45 (P = < 0.001) | 0.56 (P = < 0.001) | 0.56 (P = < 0.001) |
QSM values were adjusted for age and time from scan to death
Bold values indicate statistical significance at p < 0.05
%AO, percent area occupied; QSM, quantitative susceptibility mapping