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. 2026 Feb 5;13:1730036. doi: 10.3389/fmed.2026.1730036

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Copyright © 2026 Ramadan, Bagatadah, Marwah, Bahawi, Mriani, Alshamrani, Alzaid, Aboulola and Aboalola.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Line graph showing temporal trends in emergency department visits and admissions from 2016 to 2021. ED visits, represented by an orange line, increase sharply from 9.2 in 2016 to 38.8 in 2021. Admissions, shown with a blue dashed line, rise gradually from 6.3 in 2016 to 13.6 in 2021. The largest spike for visits occurs in 2018. — Incidence of ED and admission visits among sickle cell disease patients from 2016 to 2021 (N = 691). Lines represent mean annual counts per patient with shaded 95% confidence intervals. ED visits (solid orange line) rose sharply from 9.2 in 2016 to 38.8 in 2021, while admissions (dashed blue line) increased more gradually from 6.3 to 13.6. Trends were assessed using Poisson regression with year as a continuous variable to evaluate temporal change in healthcare utilization.