Table 3. Comparative analysis of CoS and CoR familial Mediterranean fever patients.
| Paediatric-diagnosis patients (n=170) | Adult-diagnosis patients (n=66) | |||||
|---|---|---|---|---|---|---|
| CoS (n=85) |
CoR (n=85) |
P value | CoS (n=33) |
CoR (n=33) |
P value | |
| Female, n (%) | 51 (60) | 51 (60) | >0.999 | 16 (48.5) | 16 (48.5) | >0.999 |
| Age at symptom onset, mean (SD) (years) | 3.7 (3.3) | 3.84 (3.5) | 0.984 | 8.46 (6.2) | 7.74 (6.4) | 0.626 |
| Age at first symptoms ≤3 years, n (%) | 48 (56.5) | 46 (54.1) | 0.877 | 7 (21.2) | 6 (18.2) | >0.999 |
| Age at diagnosis, mean (SD) (years) | 6.76 (4.6) | 6.78 (4.6) | 0.976 | 32.98 (11.6) | 33.08 (11.8) | 0.995 |
| Attack duration, mean (SD) (days) | 2.59 (1.1) | 2.65 (1.0) | 0.689 | 3.39 (2.5) | 3.29 (1.5) | 0.187 |
| Frequency of attacks ≥1 per month, n (%) | 53 (62.4) | 71 (83.5) | 0.003 | 16 (48.5) | 20 (60.6) | 0.458 |
| Clinical findings, n (%) | ||||||
| Fever ELE Arthralgia Arthritis Abdominal pain Chest pain |
59 (69.4) 28 (32.9) 55 (64.7) 13 (15.3) 76 (89.4) 47 (55.3) |
74 (87.0) 41 (48.2) 67 (78.8) 35 (41.2) 81 (95.3) 40 (47.1) |
0.009 0.061 0.061 <0.001 0.248 0.357 |
23 (69.7) 15 (45.5) 16 (48.5) 7 (21.2) 26 (78.8) 12 (36.4) |
27 (81.8) 15 (45.5) 28 (84.9) 13 (39.4) 33 (97) 32 (97) |
0.389 >0.999 0.004 0.181 0.054 >0.999 |
| TURPAID score, mean (SD) | 2.52 (0.6) | 2.84 (0.7) | 0.006 | 2.24 (0.6) | 2.45 (0.6) | 0.177 |
| Patients with TURPAID score ≥2, n (%) | 76 (89.4) | 82 (96.5) | 0.132 | 25 (75.8) | 29 (87.9) | 0.339 |
Variables in bold are statistically significant.
CoR, colchicine-resistance; CoS, colchicine-sensitive; ELE, erysipela-like erythema; TURPAID, Turkish Paediatric Autoinflammatory Diseases.