Table 1.
Demographic and baseline characteristics of the study sample, summarizing age, sex, education level and other key variables relevant to participant composition and group comparability
| Characteristics | PA group (n = 17) |
AA group (n = 17) |
All participants (n = 34) |
|
|---|---|---|---|---|
| Age (years) | Mean (s.d.) | 33.1 (9.73) | 32.5 (8.60) | 32.8 (9.05) |
| Range | 21–52 | 24–53 | 21–53 | |
| Sex, n (%) | Female | 6 (35.3) | 4 (23.5) | 10 (29.4) |
| Male | 11 (64.7) | 13 (76.5) | 24 (70.6) | |
| Race, n (%) | Asian | 1 (5.9) | 1 (5.9) | 2 (5.9) |
| Black or African American | – | 1 (5.9) | 1 (2.9) | |
| White | 15 (88.2) | 15 (88.2) | 30 (88.2) | |
| Other | 1 (5.9) | – | 1 (2.9) | |
|
Ethnicity, n (%) |
Hispanic or Latino | 1 (5.9) | – | 1 (2.9) |
| Not Hispanic or Latino | 16 (94.1) | 17 (100.0) | 33 (97.1) | |
| Body mass index (kg m−2) | Mean (s.d.) | 24.98 (3.796) | 24.62 (3.855) | 24.80 (3.772) |
| Range | 19.6–33.2 | 19.7–32.6 | 19.6–33.2 | |
| Cigarettes (daily) | n | 1 | 4 | 5 |
| Range | 3 | 2–10 | 2–10 | |
| Alcohola (units per week) | n | 13 | 15 | 28 |
| Mean | 4.4 | 6.4 | 5.5 | |
| Range | 1–14 | 1–18 | 1–18 | |
| Years with depression | Mean (s.d.) | 13.0 (9.4) | 7.71 (6.8) | 10.4 (8.5) |
| Median | 10 | 6 | 7.5 | |
| Range | 2–30 | 1–30 | 1–31 | |
| Weaned off AD before dosing | n | 4 | 4 | 8 |
| Prior psychedelic use | n | 5 | 6 | 11 |
| HAM-D score day −1 | Mean (s.d.) | 18.65 (1.32) | 19.65 (2.12) | 19.15 (1.81) |
| Range | 17–21 | 17–22 | 17–22 | |
| MADRS score day −1 | Mean (s.d.) | 26.3 (6.1) | 25.5 (7.2) | 25.9 (6.6) |
| Range | 13–34 | 12–38 | 12–38 | |
aInclude only those who consume alcohol.