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. 2026 Feb 11;14(1):84. doi: 10.3390/medsci14010084
MASLD metabolic dysfunction-associated steatotic liver disease
CVD cardiovascular disease
ROS reactive oxygen species
LDL low-density lipoprotein
HCC hepatocellular carcinoma
LDL-C how-density lipoprotein cholesterol
SAMs statin-associated muscle symptoms
ASCVD atherosclerotic cardiovascular disease
MASH metabolic dysfunction-associated steatohepatitis
NAC N-acetylcysteine
HSC hepatic stellate cell
RCT randomised controlled trial
AUC area under the curve
Cmax maximum plasma concentration
KLF-2 Kruppel-like factor 2
HVPG hepatic venous pressure gradient
NSBB non-selective beta blocker
CK creatinine kinase
ETOH ethanol
ULN upper limit of normal
NODM new-onset diabetes mellitus
FDA Food and Drug Administration
CYP cytochrome P450
P-gp P-glycoprotein
STAREE STAtin Therapy for Reducing Events in the Elderly
DILI drug-induced liver injury
CT computed tomography
LFTs liver function tests
1H-MRS proton magnetic resonance spectroscopy
NAS NAFLD activity score
FIB-4 Fibrosis 4 Index for Liver Fibrosis
IHCL intrahepatocellular lipid
NAFLD non-alcoholic fatty liver disease
MRI-PDFF magnetic resonance imaging-derived proton density fat fraction
HCV hepatitis C virus
HBV hepatitis B virus
AIH autoimmune hepatitis
BD twice daily
PBC primary biliary cholangitis
PON-1 paraoxanase-1, PPAR
PPAR-α peroxisome proliferator-activated receptor alpha
FAO fatty acid oxidation
eNOS endothelial nitric oxide synthase
NO nitric oxide
TNF-α tumour necrosis factor alpha
IL-6 interleukin 6
TGF-β transforming grown factor beta
LSEC liver sinusoidal endothelial cell