Table 2.

Multivariable Cox Regression Analysis Evaluating the Risk of V142I Carriers for Developing the Studied Outcomes

	HR	95% CI	P Value
HF/CM	1.20	1.10-1.31	<0.001
AF/AFL	1.26	1.13-1.40	<0.001
CTS	1.43	1.30-1.57	<0.001
SS	1.17	1.07-1.28	<0.001
Neuropathy	1.24	1.13-1.36	<0.001

Adjusted for age, sex, type 2 diabetes, hypertension, body surface area, and smoking status.

AF = atrial fibrillation; AFL = atrial flutter; CM = cardiomyopathy; CTS = carpal tunnel syndrome; HF = heart failure; SS = spinal stenosis.