Figure 1.

Hst5 accelerated corneal wound closure rates in a murine corneal alkali burn injury model. (A) Slit-lamp images of murine corneas using a cobalt filter and fluorescein dye staining of the wounded areas were shown among the experimental groups (n = 5 for each group) (Hst5 [20 µM]). (B) Wound areas at multiple time points were measured using ImageJ software. Measurement of percentage remaining corneal wound area at 18 and 24 hours compared to baseline showed statistically significant improvement in Hst5 treated group compared to BSS. Un (Uninjured, Baseline). Statistical significance was determined by a two-way ANOVA with multiple comparison. *P < 0.05. % Wound area = (wound area at time x/wound area at time 0) × 100.