Figure 5.

Alkali burn injury-induced corneal neovascularization in corneas with or without Hst5 treatment. (A) Representative white-light images show corneal neovascularization after alkali injury in eyes treated three times daily with either BSS or Hst5 (20 µM). A notable reduction in neovascularization is observed in corneas treated with Hst5. (B) Neovascularization was graded on a scale from 0 to 4, as described in the Material and Methods section. Results are presented as floating bars (min to max) with the mean indicated (—), based on five animals per group. Un = Uninjured, Baseline. Statistical significance was determined by two-way ANOVA with multiple comparisons. *P < 0.05, ***P < 0.001.