Table 3.
Changes in visual analog scale (VAS) resting pain scores over time for left, right, and all treated knees
| Timepoint | Knee | N | VAS (mean ± SD) |
Paired t-test vs. baseline (p-value) |
|---|---|---|---|---|
| V1 | Left | 54 | 41.41 ± 23.72 | – |
| V5 | 50 | 23.58 ± 19.12 | < 0.001 | |
| V7 | 50 | 14.10 ± 18.11 | < 0.001 | |
| V1 | Right | 59 | 41.64 ± 22.69 | – |
| V5 | 55 | 25.87 ± 20.28 | < 0.001 | |
| V7 | 54 | 18.89 ± 21.78 | < 0.001 | |
| V1 | All knees | 113 | 41.53 ± 23.08 | – |
| V5 | 105 | 24.78 ± 19.68 | < 0.001 | |
| V7 | 104 | 16.59 ± 20.15 | < 0.001 |
VAS scores for resting pain were assessed using a 100-mm visual analog scale at baseline (Visit 1), Week 6 (Visit 5), and Week 28 (Visit 7). Data are presented as mean ± SD. Paired t-tests comparing each follow-up timepoint with baseline showed statistically significant reductions in pain for all groups (p < 0.001)