Table 2.

Incidence rate (IR/1000 person-years) and proportions of herpes zoster cases with complications

	General adults		Group with increased- risks
	N (%)a	IR (95% CI)	N (%)b	IR (95% CI)
Complications	2975 (11.51)	0.55 (0.53, 0.57)	169 (13.72)	2.21 (1.89, 2.57)
PHNc	2317 (8.96)	0.43 (0.41, 0.45)	134 (10.88)	1.75 (1.47, 2.08)
Herpes zoster ophthalmicus	403 (1.56)	0.07 (0.07, 0.08)	18 (1.46)	0.24 (0.14, 0.37)
Zoster encephalitis	153 (0.59)	0.03 (0.02, 0.03)	10 (0.81)	0.13 (0.06, 0.24)
Disseminated zoster	16 (0.06)	0.00 (0.00, 0.00)d	1 (0.08)	0.01 (0.00, 0.07)
HZ with other complications	187 (0.72)	0.03 (0.03, 0.04)	13 (1.06)	0.17 (0.09, 0.29)

^aPercentages were based on the total number of herpes zoster cases (N = 25,855)

^bPercentages were based on the total number of herpes zoster cases in increased-risk adults (N = 1232)

^cPHN was defined by ICD-10 B02.2 × without a 90-day threshold. Identification was based on B02.2 × codes; duration criterion was not enforced

^d0.30 (0.17, 0.48)/100,000 PY

95% CIs were calculated using exact Poisson limits

Multiple complications per individual were allowed

CI confidence interval, PHN postherpetic neuralgia, HZ herpes zoster