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. 2026 Feb 20;26:75. doi: 10.1186/s12906-026-05277-7

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© The Author(s) 2026

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Effects of CH seed on polyQ35 cluster formation in muscle cells of the body wall in AM140 worms. a Untreated control. b Solvent control. c CH 50 µg/ml. d CH 100 µg/ml. e CH 200 µg/ml. Scale bar = 100 μm. f At all the tested doses, CH seed decreased the number of polyQ35 clusters. The results are denoted by the mean cluster number ± SEM for three different trials, 30 worms/group. Data analysis was performed with one-way ANOVA followed by the Bonferroni correction (post-hoc). ***p < 0.001 versus the solvent control group