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. 2026 Feb 3;27:176. doi: 10.1186/s13063-026-09491-z
Title {1} Effects of Advanced Trauma Life Support® Training Compared with Standard Care on Adult Trauma Patient Outcomes (ADVANCE TRAUMA): A Stepped-Wedge Cluster Randomised Trial
Trial registration {2a and 2b} Clinical Trials Registry – India (CTRI/2024/07/071336), ClinicalTrials.gov (NCT06321419, 2024–03–20)
Protocol version {3} 1.5.0, 2025–06–12
Funding {4} Swedish Research Council (reg. no. 2023–03128) and Laerdal Foundation (reg. no. 2023–0297)
Author details {5a}

Samriddhi Ranjan (SR)

The George Institute for Global Health, New Delhi, India

Sara Fälth (SF)

Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden

Prashant Kharat (PK)

The George Institute for Global Health, New Delhi, India

Abhinav Bassi (AB)

The George Institute for Global Health, New Delhi, India

G D Bakhshi (GB)

Department of General Surgery, Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals, Mumbai, India

Debojit Basak (DB)

Institute of Post Graduate Medical Education and Research, Kolkata, India

Johanna Berg (JB)

• Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden

• Emergency Medicine, Department of Internal and Emergency Medicine, Skåne University Hospital, Malmö, Sweden

Shamita Chatterjee (SC)

Department of General Surgery, Institute of Post Graduate Medical Education and Research, Kolkata, India

Li Felländer-Tsai (LFT)

• Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden

• Department of Reconstructive Orthopedics, Karolinska University Hospital, Stockholm, Sweden

Karla Hemming (KH)

Institute of Applied Health Research, University of Birmingham, Birmingham, UK

Vivekanand Jha (VJ)

The George Institute for Global Health, New Delhi, India

Jessica Kasza (JK)

School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

Monty Khajanchi (MK)

Department of Surgery, Seth G. S. Medical College and K.E.M. Hospital, Mumbai, India

James Martin (JM)

Institute of Applied Health Research, University of Birmingham, Birmingham, UK

Anurag Mishra (AM)

Department of General Surgery, Maulana Azad Medical College, New Delhi, India

Anna Olofsson (AO)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Nobhojit Roy (NR)

• Program for Global Surgery and Trauma, The George Institute for Global Health, New Delhi, India

• Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden

Rajdeep Singh (RS)

Department of General Surgery, Maulana Azad Medical College, New Delhi, India

Kapil Dev Soni (KDS)

Critical and Intensive Care, JPN Apex Trauma Center, All India Institute of Medical Sciences, New Delhi, India

Martin Gerdin Wärnberg (MGW)

• Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden

• Perioperative Medicine and Intensive Care, Karolinska University Hospital, Solna, Sweden

Name and contact information for the trial sponsor {5b}

Karolinska Institutet, 171 77 Stockholm, Sweden

Contact person: Martin Gerdin Wärnberg, martin.gerdin@ki.se

Role of sponsor {5c} This is an investigator-initiated study. The sponsor contact person is also the principal investigator. The funding bodies had no role in the design of this trial, the preparation of it, nor the decision to submit this protocol for publication