Table 2.
Characteristics of tightest binding aptamers
| Aptamer | No. sequences
|
Kd, nM | koff, min−1 | Pool of origin | |
|---|---|---|---|---|---|
| Unique | Total | ||||
| 9-4 | 1 | 10 | 25 | 0.0027 | Designed |
| 10-10 | 1 | 1 | 28 | 0.01 | Designed |
| Class I | 13 | 16 | 60–300 | 0.06 | 12 designed/1 random |
| 10-59 | 1 | 6 | 200 | 0.027 | Random |
| 9-12 | 1 | 9 | 250 | 0.03 | Random |
| 10-24 | 1 | 1 | 250 | — | Designed |
| 10-6 | 1 | 1 | 500 | — | Designed |