Table 1.
Comparison of adolescent PCOS and control groups in terms of demographic, anthropometric measurements and hormonal values
| Parameters | Control(n = 44) | PCOS (n = 45) |
T, z | p |
|---|---|---|---|---|
| Age (years) | ||||
| (Median (IQR)) | 17(2) | 17(1) | 1.392 | 0.164 |
| Age at menarche (years) | ||||
| (Median (IQR)) | 12(1) | 13 (1) | 1.387 | 0.166 |
| Cycle duration (day) | ||||
| (Median (IQR)) | 30 (2) | 60(55) | 6.961 | < 0.001 |
| Dysmenorrhea, n(%) | ||||
| No | 19 (%43.1) | 22 (%48.5) | 0.292 | 0.589 |
| Yes | 25 (%56.8) | 23 (%51.1) | ||
| Menstrual irregularity, n (%) | ||||
| No | 32 (%72.7) | 8 (%17.7) | 27.147 | < 0.001 |
| Yes | 12 (%27.2) | 37 (%82.2) | ||
| Hirsutism. n (%) | ||||
| No | 44 (%100.0) | 17 (%37.7) | 39.945 | < 0.001 |
| Yes | 0 (%0.0) | 28 (%62.2) | ||
| Acne, n (%) | ||||
| No | 35 (%79.5) | 20 (%44.4) | 26.313 | < 0.001 |
| Mild | 9(%20.4) | 9 (%2) | ||
| Modarate | 0 (%0) | 8 (%17.7) | ||
| Severe | 0 (%0) | 8 (%17.7) | ||
| Presence of PCOM on ultrasonography, n (%) | ||||
| No | 42(%95.4) | 13(%28.2) | 41.756 | < 0.001 |
| Yes | 2(%4.5) | 32(%71.1) | ||
| Body mass index (kg/m2) | ||||
| (Median (IQR)) | 21.10 (5.40) | 23.39 (7.34) | 1.784 | 0.074 |
| Ferriman-Gallwey Score | ||||
| (Median (IQR)) | 3 (2) | 15 (9) | 8.132 | < 0.001 |
| Waist circumference (cm) | ||||
| (Median (IQR)) | 71 (9) | 76.00 (14) | 2.526 | 0.012 |
| Hip Circumference (cm) | ||||
| (Mean ± SD) | 95.28 ± 7.22 | 98.37 ± 10.56 | 1.820* | 0.072 |
| Waist / Hip Circumference | ||||
| (Median (IQR)) | 0.74 (0.07) | 0.76 (0.11) | 1.379 | 0.168 |
| Neck circumference (cm) | ||||
| (Median (IQR)) | 31 (3) | 32 (3) | 2.235 | 0.025 |
| Lean body mass index (kg) | ||||
| (Mean ± SD) | 43.41 ± 4.72 | 44.85 ± 5.53 | 0.849* | 0.398 |
| FSH (IU/L) | 6.33 (2.28) | 5.30 (2.41) | 2.396 | 0.017 |
| LH (IU/L) | 8.28 (5.72) | 8.24 (8.92) | 0.636 | 0.525 |
| SHBG (nmol/L) | 35.80 (19.90) | 25.10 (28.00) | 3.024 | 0.002 |
| DHEA-S(µg/dl) | 204 (153) | 185 (167) | 0.501 | 0.617 |
| Free Testosterone (pg/ml) | 2.50 (1.76) | 2.29 (1.57) | 0.111 | 0.912 |
| FAİ | 2.62 (2.09) | 4.49 (6.07) | 2.864 | 0.004 |
| AMH (mg/L) | 2.51 (2.46) | 5.37 (5.07) | 4.620 | < 0.001 |
| Fasting Insulin Level (mU/L) | 11.60 (8.75) | 13.6 (16.12) | 0.915 | 0.360 |
| Fasting Blood Glucose (mg/dl) | 83 (10) | 82 (13) | 0.834 | 0.404 |
| HOMA-IR | 2.25 (1.76) | 2.62 (3.32) | 1.145 | 0.252 |
| 25-OH Vitamin D (nmol/L) | 10 (4) | 11 (11) | 0.462 | 0.665 |
*t value IQR Inter quantile range, SD Standard deviation, kg Kilogram, m Meter, cm Centimeter, PCOS Polycystic ovary syndrome, PCOM Polycystic ovary morphology, FSH Follicle-stimulating hormone, LH Luteinizing hormone, SHBG Serum sex hormone binding globulin, DHEA-SO4 Dehydroepiandrosterone sulfate, FAI Free Androgen Index, AMH Anti-müllerian hormone, HOMA-IR Homeostatic Model Assessment of Insulin Resistance, 25-OH Vitamin D 25-hydroxy vitamin D