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Summary of cross-stimulation and cross-recognition properties of NY-ESO-1 peptides
| Peptide used as target in T cell assay | Peptide used for in vitro stimulation of T cells
|
||
|---|---|---|---|
| S9C | S11L | L9L | |
| Patients with natural immunity to NY-ESO-1 | |||
| S9C | + | + | − |
| S11L | + | + | − |
| L9L | − | − | − |
| Vaccinated patients responding only to peptide S11L (no preexisting immunity) | |||
| S9C | − | − | − |
| S11L | − | + | + |
| L9L | − | + | + |
| Vaccinated patients responding to both peptides S9C and S11L | |||
| S9C | + | + | − |
| S11L | + | + | + |
| L9L | − | + | + |
