TABLE 2.

Structural and functional annotation of the eight OSCC-associated variants selected for downstream modeling and docking. For each gene, the corresponding SNP (rsID), amino-acid substitution, and PDB ID are shown. References indicate the primary literature that determined the structure of these proteins experimentally.

Protein	PDB ID	Variant (rsID)	Amino acid substitution	References
ATM	7SIC	rs1801516	D1853N	Warren and Pavletich (2022)
XRCC1	2D8M	rs1799782 and rs25487	R194W and Q399R	Nagashima et al. (2006)
FLT3	3QS7	rs1933437	T227M	Verstraete et al. (2011)
MUTYH	8FAY	rs3219489	Q310H	Trasvina-Arenas et al. (2024)
XPC	8EBU	rs2228000 and rs2228001	A499V and Q939K	Kim et al. (2023)
MSH3	8OLX	rs1650697	I79V	Lee et al. (2024)