Table 2.
Bivariate correlation analyses of sphingosine-1-phosphate with baseline data. Abbreviations: aspirin, acetylsalicylic acid; HbA1c, glycated hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein. * indicates statistical significance after Bonferroni-correction for multiple comparisons
| Cross-sectional correlation analyses of sphingosine-1-phosphate | ||||
|---|---|---|---|---|
| Aspirin, yes (n = 270) | Aspirin, no (n = 104) | |||
| Variable | Spearman’s ρ | p-value | Spearman’s ρ | p-value |
| Age | − 0.127 | 0.038 | − 0.253 | 0.010 |
| Body mass index | 0.018 | 0.778 | 0.070 | 0.497 |
| Hematocrit | 0.211 | < 0.001* | 0.258 | 0.009 |
| Leucocytes | 0.071 | 0.247 | 0.221 | 0.025 |
| Platelets | 0.362 | < 0.001* | 0.296 | 0.003* |
| HbA1c | − 0.002 | 0.978 | 0.060 | 0.551 |
| Triglycerides | 0.211 | < 0.001* | 0.162 | 0.108 |
| HDL-cholesterol | − 0.050 | 0.415 | 0.049 | 0.626 |
| LDL-cholesterol | 0.258 | < 0.001* | 0.203 | 0.044 |
| Creatinine | − 0.071 | 0.246 | − 0.046 | 0.649 |
| Soluble P-selectin | 0.254 | < 0.001* | 0.117 | 0.240 |
| Thromboxane B2 | 0.158 | 0.041 | 0.020 | 0.885 |