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. 2026 Feb 2;14(2):349. doi: 10.3390/biomedicines14020349
MDH Mammary ductal hyperplasia
DCIS ductal carcinoma in situ
RR relative risk
UDH usual ductal hyperplasia
OR odds ratio
ADH atypical ductal hyperplasia
ALH atypical lobular hyperplasia
FEA flat epithelial atypia
MRI Magnetic Resonance Imaging
LCIS lobular in situ carcinoma
PIK3CA Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
BRCA1/2 Breast CAncer gene 1/2
TP53 Tumor Protein 53
DNA Deoxyribonucleic Acid
K-AKT-mTOR Phosphoinositide 3-kinase-AKR mouse thymoma-Mechanistic (mammalian) Target of Rapamycin
CDH1 Cadherin-1
TBX3 T-box transcription factor 3
CCLs Columnar cell lesions
ER Estrogen Receptor
NF1 Neurofibromin 1
GATA Glutamyl aminotransferase subunit A
MAP3K1 Mitogen-activated protein kinase kinase kinase 1
CBFB Core-Binding Factor, Beta Subunit
16q LOH 16 q Loss of Heterozygosity
PTEN phosphatase and tensin homolog
IBC invasive breast cancers
ERBB2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
HR hormone receptors
RUNX1 Runt-related transcription factor 1
FOXA1 Forkhead box protein A1
KMT2C (MLL3)/KMT2D (MLL2) type 2 lysine methyltransferases
ARID 1A/ARID 1B AT-Rich Interaction Domain 1A Gene/AT-Rich Interaction Domain 1B Gene
NCOR1/NCOR2 Nuclear Receptor Co-Repressor 1/Nuclear Receptor Co-Repressor 2
CREBBP/EP300 CAMP Response Element-Binding-Binding Protein/E1A-binding protein P300
NOTCH1 Neurogenic locus notch homolog protein 1
RNAs Ribonucleic acid
RASSF1A Ras Association Domain Family 1, isoform A
APC Adenomatous Polyposis Coli
TWIST1 Twist Family BHLH Transcription Factor 1
HIN1 Hypermethylated in Cancer 1
p16INK4a Cyclin-Dependent Kinase Inhibitor 2A
TP53 Tumor Protein p53
SOCS1 Suppressor of Cytokine Signaling 1
CGH Comparative genomic hybridization
FISH Fluorescence in situ hybridization
HER 2 Human Epidermal Growth Factor Receptor 2
IHC Immunohistochemistry
MMP-1 Matrix metalloproteinase-1
PAS periodic acid-Schiff
RRM2 Ribonucleotide Reductase Regulatory Subunit M2
TOP2A Topoisomerase II Alpha
PBK PDZ-Binding Kinase
MELK Maternal Embryonic Leucine Zipper Kinase
NUSAP1 Nucleolar and Spindle-Associated Protein 1
AH atypical hyperplasia
H-E haematoxylin and eosin
PCR polymerase chain reaction
HIF-1alpha Hypoxia-Inducible Factor 1 alpha
GLUT1 Glucose Transporter 1
CAIX Carbonic Anhydrase IX
JAG1 Jagged 1
RB Retinoblastoma protein
LOH Loss of heterozygosity
TNM Tumor–Node–Metastasis staging system
SMA and smooth muscle actin
CK5/6 Cytokeratin 5/6
FHIT Fragile Histidine Triad
WWOX WW Domain–Containing Oxidoreductase
CGH Comparative Genomic Hybridization.
c-erbB-2 HER2
SIR Signal-to-Intensity Ratio
ESR1 Estrogen receptor 1
PGR Progesterone receptor
Ki-67 Tumor proliferation
EMT epithelial-to-mesenchymal transition
Wnt Wingless Int-1
LOI Loss of imprinting
H3K27me3 Histone 3 lysine 27 trimethylation
HM13 Histocompatibility minor 13
KCNQ9 Potassium voltage-gated channel subfamily Q member 9
IGF2 Insulin-like growth factor 2
PEG1/MEST Paternally expressed gene 1/Mesoderm-specific transcript
TASK3 TWIK-related acid-sensitive potassium channel 3
KCNK9 DMR Potassium channel subfamily K member 9 differentially methylated region
TGF-β Transforming Growth Factor beta
BMP Bone Morphogenetic Protein
DDL Delta-like ligand (DLL)
SOX2 SRY (Sex-determining Region Y)-Box 2
OCT4 Octamer-binding transcription factor 4
CSCs cancer stem cells
IL-6 Interleukin 6
PKB Protein Kinase B (also known as AKT)
NF-κB Nuclear Factor kappa-light-chain-enhancer of activated B cells
MRP2 Multidrug Resistance-associated Protein 2
CTNNB1 Catenin Beta 1 (β-catenin)
AXIN Axis Inhibition Protein
SFRP1-5 Secreted Frizzled-Related Proteins 1–5
WIF1 Wnt Inhibitory Factor 1
DKK1 Dickkopf-related protein 1
SRY Sex-determining Region Y
EZH2 Enhancer of Zeste Homolog 2
DACT3 Disheveled-binding Antagonist of β-catenin 3
H3K4me3 Histone 3 lysine 4 trimethylation
Suz12 Suppressor of Zeste 12
SirT1 Sirtuin 1
BMI1 B lymphoma Mo-MLV insertion region 1 homolog
Lef1 Lymphoid Enhancer-binding Factor 1
Slug Snail family transcriptional repressor 2
ZEB1 Zinc Finger E-box-binding Homeobox 1
Snail Snail family transcriptional repressor 1
ZEB2 Zinc Finger E-box-binding Homeobox 2
FOXC2 Forkhead Box C2
TWIST2 Twist family bHLH transcription factor 2
CD44 Cluster of Differentiation 44
CD133 Cluster of Differentiation 133
SIP1 Smad Interacting Protein 1
BMP-6 Bone Morphogenetic Protein 6
ECM extracellular matrix
TME tumor microenvironment
α-SMA alpha-smooth muscle actin
CAFs cancer-associated fibroblasts
HGF hepatocyte growth factor
MET receptor Mesenchymal–Epithelial Transition receptor
MCF10 original non-tumorigenic human mammary epithelial cell line
HGF/MET Hepatocyte Growth Factor/MET receptor signaling pathway
HFD high-fat diet
CEACAM1 in carcinoembryonic antigen-related cell adhesion molecule 1
MVD Microvessel Density
PKC-α Protein Kinase C alpha
MEK3 Mitogen-activated protein kinase kinase 3
AMPKα AMP-activated protein kinase alpha subunit
TILs tumor-infiltrating lymphocytes
Foxp3 Forkhead box P3
Tregs regulatory T cells
S100A9 S100 calcium-binding protein A9
PMN polymorphonuclear neutrophils
Ly6G+ Lymphocyte antigen 6 complex, locus G positive
HIF 1α 1hypoxia-inducible factor-1α
VEGF vascular endothelial growth factor
DCE-MRI Dynamic contrast-enhanced MRI
sEVs small extracellular vesicles
PMN-MDSCs polymorphonuclear myeloid-derived suppressor cells
IGF Insulin-like growth factor
MAPK Mitogen-Activated Protein Kinase
ET Endocrine Therapy
ROS reactive oxygen species
GPER G protein-coupled estrogen receptor
EDCs Endocrine-disrupting chemicals
BPA Bisphenol A
DDT Dichlorodiphenyltrichloroethane
CYP19A1 Cytochrome P450 Family 19 Subfamily A Member 1
PM particulate matter
PAHs polycyclic aromatic hydrocarbons