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. 2026 Feb 12;48(2):202. doi: 10.3390/cimb48020202
AP-1 Activated protein-1
ADCC Antibody-dependent cell-mediated cytotoxicity
CAR-T Chimeric antigen receptor T-cell
CTL Cytotoxic T cells
CTLA-4 Cytotoxic T lymphocyte-associated antigen-4
CRS Cytokine release syndrome 
DC Dendritic cells
DAMPs Damage-associated molecular patterns
EMT Epithelial-mesenchymal transition
GM-CSF Granulocyte-macrophage colony-stimulating factor
GZMB Granzyme B
PRF1 Perforin 1
IFNG Interferon gamma
IL-2 Interleukin-2
IRAK1 Interleukin-1 receptor-associated kinase 1
CAFs Cancer-associated fibroblasts
ST2L Soluble ST2 (long form)
MAPK Mitogen-activated protein kinase
TAK1 Transforming growth factor-β-activated kinase 1
CD8+ T cell CD8-positive T cell
IRF Interferon regulatory factor
IL-12 Interleukin-12
TRAP TNF receptor-associated protein
RIP Receptor-interacting protein
IL-18 Interleukin-18
IL-18Rs IL-18 receptors
IL-18BP IL-18-binding proteins
ICIs Immune checkpoint inhibitors
IFN-γ Interferon-γ
PBMC Peripheral blood mononuclear cell
JNK c-Jun endonucleotide-binding kinase
MDSCs Myeloid-derived suppressor cells
MHC Major histocompatibility complex
MMP-2 Matrix metalloproteinase-2
MMPs Matrix metalloprMatrix metalloproteinasesoteinases
MyD88 Myeloid differentiation factor 88
NK Natural killer
NF-κB Nuclear factor-κB
PD-1 Programmed death receptor-1
IRAK-4 Interleukin-1 Receptor-Associated Kinase
IRAK-1 TRIF-related adaptor molecule
TRAM Toll/Interleukin-1 Receptor domain
TIR IκB Kinase
IKKα IκB Kinase Alpha
IKKβ IκB Kinase Beta
TAB1/2 TAK1 Binding Protein 1/2
IKKγ/NEMO IκB Kinase Gamma
IκBα Inhibitor of Nuclear Factor κB Alpha
PI3K Phosphatidylinositol 3-kidronase
PD-L1 Programmed cell death ligand-1
PAMPs Pathogen-associated molecular patterns
TRAF-6 TNF-α receptor-associated factor-6
TME The tumor microenvironment
TAMs Tumor-associated macrophages
TGF-β Transforming growth factor-β
Tregs Regulatory T cells
VEGF Vascular endothelial growth factor