| Abbreviation | Full term |
| AP site | apurinic/apyrimidinic site |
| ASO(s) | antisense oligonucleotide(s) |
| AuNP(s) | gold nanoparticle(s) |
| Cas9 | CRISPR-associated protein 9 |
| CHA | catalytic hairpin assembly |
| CLDz2 | click-ligation deoxyribozyme 2 (DNAzyme-catalyzed triazole ligation) |
| COPD | chronic obstructive pulmonary disease |
| CRISPR | clustered regularly interspaced short palindromic repeats |
| CT | computed tomography |
| DMSO | dimethyl sulfoxide |
| Dz-seq (DZ-seq) | deoxyribozyme sequencing (high-throughput activity profiling by sequencing) |
| EPR | enhanced permeability and retention (effect) |
| FAM | 6-carboxyfluorescein (fluorophore label) |
| GalNAc | N-acetylgalactosamine |
| G4 | G-quadruplex |
| GATA-3 | GATA binding protein 3 |
| GPX4 | glutathione peroxidase 4 |
| HCR | hybridization chain reaction |
| HRV | human rhinovirus |
| HT-SELEX | high-throughput systematic evolution of ligands by exponential enrichment |
| LAMP | loop-mediated isothermal amplification |
| LFA | lateral flow assay |
| LNA | locked nucleic acid |
| lncRNA(s) | long non-coding RNA(s) |
| m1A | N1-methyladenosine |
| m6A | N6-methyladenosine |
| mRNA | messenger RNA |
| miRNA | microRNA |
| MOE | 2′-O-methoxyethyl |
| MOF(s) | metal–organic framework(s) |
| MRI | magnetic resonance imaging |
| MsPA | mesyl phosphoramidate |
| NF-κB | nuclear factor kappa B |
| NIR | near-infrared |
| NLRP3 | NLR family pyrin domain containing 3 |
| PAGE | polyacrylamide gel electrophoresis |
| PCR | polymerase chain reaction |
| PD-L1 | programmed death-ligand 1 |
| PEG | polyethylene glycol |
| PET | positron emission tomography |
| PK-PD | pharmacokinetics/pharmacodynamics |
| PS | phosphorothioate |
| PDT | photodynamic therapy |
| RIP3 | receptor-interacting protein kinase 3 |
| RNA | ribonucleic acid |
| SB010 | GATA-3 mRNA-targeting therapeutic DNAzyme candidate |
| SELEX | systematic evolution of ligands by exponential enrichment |
| SNP(s) | single-nucleotide polymorphism(s) |
| SuFEx | sulfur(VI) fluoride exchange |
| Th2 | type 2 helper T |
| TNA | threose nucleic acid |
| TNF-α | tumor necrosis factor alpha |
| VEGF | vascular endothelial growth factor |
| VEGFR2 | vascular endothelial growth factor receptor 2 |
| XNA | xeno nucleic acid |