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. 2002 Aug 27;99(19):12108–12113. doi: 10.1073/pnas.182412599

Table 3.

Cofactor dependency of recombinant 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase

Omitted compound Relative activity, %
None 100
Pamidronate 42
Co2+ 20
FAD 17
NADH 12

Reaction conditions were as described under Experimental Procedures.