MSCs	mesenchymal stromal (stem) cells
ISCT	International Society for Cell and Gene Therapy
NK	natural killer
MHC	major histocompatibility complex
HLA	human leukocyte antigen
ECM	extracellular matrix
EVs	extracellular vesicles
MISEV	Minimal Information for Studies of Extracellular Vesicles
sEVs	small extracellular vesicles
MSC-(s)EVs	MSC-derived (small) EVs
CNS	central nervous system
LPS	lipopolysaccharides
ICPs	immune checkpoint proteins
ICPLs	immune checkpoint ligands
TE	tropoelastin
VEGF	vascular endothelial growth factor
AT-MSCs	adipose (tissue)-derived stem/stromal cells
SGD	serum- and glucose-deprived
hUCMSCs	human umbilical cord mesenchymal stem cells
HUVEC	human umbilical vein endothelial cells
BMSCs	bone marrow mesenchymal stem cells
XFM	xeno-free media
LIPUS	low-intensity pulsed ultrasound
CQAs	critical quality attributes
SOCRATES, ISEV, ISCT, and ISBT	four leading international scientific societies collaborating to standardize the characterization and therapeutic use of MSC-EVs
SOCRATES	Society for Clinical Research and Translation of Extracellular Vesicles Singapore
ISEV	International Society for Extracellular Vesicles
ISBT	International Society of Blood Transfusion
GMP	good manufacturing practice
HFB	hollow-fiber bioreactor
CMSCs	placental chorionic mesenchymal stromal cells
ESC	embryonic stem cell
iMSCs	immortalized MSCs
hTERT	human telomerase reverse transcriptase
NTA	nanoparticle tracking analysis
EM	electron microscopy
TEM	transmission electron microscopy
S-hMSCs	suspension culture human mesenchymal stromal stem cells
HPLC	high-performance liquid chromatography
ATCC®	American Type Culture Collection
CSSCs	corneal stromal stem cells
HF-MSCs	human hair follicle-derived mesenchymal-like stromal cells
imCMSCs	immortalized CMSCs
E1-MYC	ESC-derived monoclonal MSC line
pMSCs	primary MSCs
PD	population doubling
PDT	population doubling time
HATMSC	immortalized AT-MSCs
GRO	growth-regulated oncogene
IL	interleukin
IGF-1	insulin growth factor 1
MMP	matrix metalloproteinase
HEPC-CB.1	human endothelial progenitor cell line originating from cord blood
bFGF	basic fibroblast growth factor
sEVs-RA	MSC-derived sEVs primed with RA serum
FBS	fetal bovine serum
TGF-β1	transforming growth factor beta 1
HGF	hepatocyte growth factor
SASP	senescence-associated secretory phenotype
BDNF	brain-derived neurotrophic factor
SV40 LT	Simian virus 40 large T antigen
RT-PCR	reverse transcription polymerase chain reaction
DRG	dorsal root ganglion
TRAP	telomeric repeat amplification protocol
imCSSCs	immortalized corneal stromal stem cells
HF-MSCs	hair follicle-derived MSCs
DPCs	dermal papilla-derived stem cells
SPECT	single-photon emission computed tomography
PET	positron emission tomography
MRI	magnetic resonance imaging
CT	computed tomography
ELISA	enzyme-linked immunosorbent assays
SEC	size-exclusion chromatography
hT-HFF cells	hTERT-immortalized fibroblasts
AML	acute myelogenous leukemia
ROCK1	Rho kinase 1