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. 2026 Jan 29;18(2):178. doi: 10.3390/pharmaceutics18020178
AUC Analytical Ultracentrifugation
CD Circular Dichroism
CQA Critical Quality Attribute
DMT 4,4-Dimethoxytrityl
FDA U.S. Food and Drug Administration
FTIR Fourier-Transform Infrared Spectroscopy
HFIP 1,1,1,3,3,3-Hexafluoroisopropanol
HPLC High Performance Liquid Chromatography
HPLC-RP Reversed-Phase High Performance Liquid Chromatography
ICP Inductively Coupled Plasma
IF Intrinsic Fluorescence
JSC Joint Stock Company
LC-MS Liquid Chromatography–Mass Spectrometry
NMR Nuclear Magnetic Resonance
OD Optical Density
PBS Phosphate-Buffered Saline
PDE Phosphodiesterase
QR Quality Range
RLD Reference Listed Drug
RNA Ribonucleic Acid
RT PCR Real-Time Polymerase Chain Reaction
SD Standard Deviation
SMA Spinal Muscular Atrophy
SMN2 Survival Motor Neuron 2 Gene
TEA Triethylamine