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. 2026 Feb 12;18(2):235. doi: 10.3390/pharmaceutics18020235
5-HTP 5-Hydroxytryptophan
AchR Acetylcholine receptor
ADP Adenosine diphosphate
Akt Protein kinase B
ARF ADP-ribosylation factor
ATP Adenosine triphosphate
B cell B lymphocyte
BBB Blood–brain barrier
BCNU Carmustine
BMAL1 Basic helix-loop-helix ARNT-like protein 1
BMEC Brain microvascular endothelial cell
CAR-T Chimeric antigen receptor T-cell
CCG Clock-controlled genes
CCNU Lomustine
CDK Cyclin-dependent kinase
CLOCK Circadian locomotor output cycles protein kaput
CM-NP Curcumin-loaded noisome nanoparticle
CNS Central nervous system
Co-MION Carboxymethylcellulose capping ligand
CPPs Cell-penetrating peptides
CRY Cryptochrome
CTX Chlorotoxin
DBP D-box binding protein
DEX Dexamethasone
DOTAP Dioleoyl-3-trimethylammonium propane
Dp44mT Di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone
ECM Extracellular matrix
ECs Endothelial cells
EGFR Epidermal growth factor receptor
FDA Food and Drug Administration
FR Folate receptor
GB Glioblastoma
GDP Guanosine diphosphate
GEF Guanine nucleotide exchange factor
GSCs Glioblastoma stem-like cells
GSK-3 Glycogen synthase kinase-3
GTP Guanosine triphosphate
HA Hyaluronic acid
HeLa Human cervical cancer cells
HIF-1α Hypoxia-inducible factor 1-alpha
HSA Human serum albumin
HSVtk Herpes simplex virus thymidine kinase
ICI Immune checkpoint inhibitors
IDH-1 Isocitrate dehydrogenase 1
IL-1β Interleukin-1ß
IL6-R Interleukin 6 receptor
INK Cyclin-dependent kinase inhibitors
LbGP Lycium barbarum
LDHA Lactate dehydrogenase A
LDLR Low-density lipoprotein receptor
LGMN Legumain
LIC Lactate-IL-1β-Clock
MDK Midkine
MDM2 Mouse double minute 2 homologue
MDMX Mouse double minute X homologue
MDSCs Myeloid-derived suppressor cells
MGMT O6-methylguanine-DNA methyltransferase
MRI Magnetic resonance imaging
NDRG N-myc downstream-regulated gene
NFIL Nuclear factor, interleukin 3-regulated.
NF-Κb Nuclear factor-κB
NK Natural killer
NMDAR N-methyl-D-aspartate receptor
NSCs Neural stem cells
OS Overall survival
PAA Poly(acrylic acid)
PBAE Poly(beta-amino ester)
PCV Vincristine
PDGFR Platelet-derived growth factor receptor
PER Period
PFS Progression-free survival
P-gp P-glycoprotein
PHR Histidine/arginine-linked polyamidoamine
PI3K Phosphoinositide 3-kinase
PIP Phosphatidylinositol phosphate
PLK1 Polo-like Kinase 1
Plofsome Polymer-locking fusogenic liposome
pRB Retinoblastoma protein
PTEN Phosphatase and tensin homologue
RAR Retinoic Acid Receptor
RAS Rat sarcoma small GTPase
REV-ERB Nuclear Receptor Subfamily 1 group D
ROR RAR-related Orphan Receptor
RORE Retinoic acid-related orphan receptor response element
RTK Receptor tyrosine kinase
SCN Suprachiasmatic nucleus
Sev Sevoflurane
siYAP YAP small interfering inhibitor
SPION Superparamagnetic iron oxide nanoparticles
STAT3 Signal transducer and activator of transcription 3
T cell T lymphocyte
TfR Transferrin receptor
TIAM1 Metastasis-inducing protein-1
TME Tumour microenvironment
TMZ Temozolomide
TTFL Translational-transcriptional feedback/feed-forward loops
VEGF Vascular endothelial growth factor
VEGFR Vascular endothelial growth factor receptor
VP Verteporfin
WHO World Health Organization