Skip to main content
. 2026 Feb 9;18(2):219. doi: 10.3390/pharmaceutics18020219
ACN Acetonitrile
ALOGPS Aqueous logP Prediction System
AUCxh Area under the plasma concentration–time curve from time zero to x hours after dosing
AUC∞ Area under the plasma concentration–time curve from time zero to infinity
BSA Bovine serum albumin
C0h Plasma concentration at time zero after dosing
Cmax Maximal plasma concentration
DMSO Dimethylsulfoxide
Fabs Fraction absorbed
Fdiss Fraction dissolved
HPLC High-performance liquid chromatography
ISG In situ gel
IV Intravenous
IVIVC In vitro–in vivo correlation
IVR In vitro release
K2.EDTA Potassium ethylenediaminetetraacetic acid
K In vitro Korsmeyer–Peppas release rate constant
LAI Long-acting injectable
LC-MS/MS Liquid chromatography–tandem mass spectrometry
L:G Lactide/glycolide ratio
Max Maximum
Min Minimum
mPEG-PLA Methoxy-poly(ethylene glycol)-co-poly(D,L-lactide)
MW Molecular weight
N Sample size
NMP N-methyl-2-pyrrolidone
n In vitro Korsmeyer–Peppas release exponent
PDA Photodiode array
PK Pharmacokinetic(s)
PLA Poly(D,L-lactide)
PLGA Poly(D,L-lactide-co-glycolide)
PLA-PEG-PLA poly(D,L-lactide)-co-poly(ethylene glycol)-co-poly(D,L-lactide)
PVDF Polyvinylidene fluoride
SD Standard deviation
SLS Sodium lauryl sulphate
t1/2 Half-life
TFA Trifluoroacetic acid
UHPLC Ultra-high-performance liquid chromatography