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. Author manuscript; available in PMC: 2026 Feb 27.
Published in final edited form as: Neurobiol Aging. 2024 May 27;141:46–54. doi: 10.1016/j.neurobiolaging.2024.05.012

Table 4.

Global cognition and gait speed as a function of CR proxies and frontal brain measures.

Education Living with someone Paid or volunteer work
β (95%CI) β (95%CI) β (95%CI)
P value P value P value
Global Cognition
CR Proxy x Frontal Cortical thickness (mm, Left hemisphere) 0.004 (−0.524, 0.532) 0.382 (−2.227, 2.991) 4.507 (1.800, 7.213)
0.988 0.774 0.001
CR Proxy x Frontal Cortical thickness (mm, Right hemisphere) 0.354 (−0.093, 0.801) −0.141 (−2.419, 2.702) 4.384 (1.761, 7.006)
0.120 0.914 0.001
Gait speed
CR Proxy x Frontal Cortical thickness (mm, Left hemisphere) 0.438 (−0.144, 1.019) 1.689 (−1.270, 4.648) 3.065 (−0.021, 6.150)
0.140 0.263 0.052
CR Proxy x Frontal Cortical thickness (mm, Right hemisphere) 0.562 (0.078, 1.046) 2.002 (−0.921, 4.925) 2.517 (−0.523, 5.558)
0.023 0.179 0.105