| MPXV | Monkeypox Virus |
| ITRs | Inverted Terminal Repeats |
| WHO | World Health Organization |
| PHEIC | Public Health Emergency of International Concern |
| OPGs | Orthologous Poxvirus Genes |
| 5mC | 5-methylcytosine |
| 5hmC | 5-hydroxymethylcytosine |
| 6mA | N6-methyladenine |
| SNPs | Single-Nucleotide Polymorphisms |