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. 2026 Feb 13;16:1687192. doi: 10.3389/fonc.2026.1687192

Table 4.

Comparison of quantitative parameters pre- and post-immunotherapy between the effective and ineffective groups.

Parameters Effective group (n=14) Ineffective group (n=5) t/Z p
pre-T1 (ms) 1965.02 ± 210.34 1808.52 ± 657.40 -0.816 0.426 a
pre-ADC (×10–6 mm2/s) 1293.10 (1108.55, 1600.56) 1279.80 (1265.50, 1328.30) -0.403 0.687 b
pre-f (×10-3%) 119.00 (86.60, 183.05) 139.90 (98.50, 140.50) -0.403 0.687 b
pre-D (×10–6 mm2/s) 1109.09 ± 208.06 1129.66 ± 119.12 0.207 0.839 a
pre-D* (×10–5 mm2/s) 825.42 ± 239.07 938.56 ± 182.10 0.957 0.352 a
post-T1 (ms) 1459.54 ± 535.96 2114.24 ± 264.63 2.586 0.019 a
post-ADC (×10–6 mm2/s) 1913.39 ± 468.25 1555.40 ± 746.42 -1.257 0.226 a
post-f (×10-3%) 244.67 ± 133.25 247.54 ± 206.11 0.036 0.972 a
post-D (×10–6 mm2/s) 1150.37 ± 360.51 1296.00 ± 313.10 0.799 0.435 a
post-D* (×10–5 mm2/s) 992.18 ± 382.20 938.54 ± 389.48 -0.268 0.792 a
ΔT1 (ms) -284.60 (-879.75, -161.23) 92.00 (6.30, 149.20) -1.913 0.056 b
ΔADC (×10–6 mm2/s) 516.25 ± 611.19 -190.60 ± 439.83 -2.358 0.031 a
Δf (×10-3%) 60.05 (-9.68, 198.68) -10.90 (-22.20, 9.00) -0.766 0.444 b
ΔD (×10–6 mm2/s) 41.29 ± 435.63 166.34 ± 328.30 0.581 0.569 a
ΔD* (×10–5 mm2/s) 166.74 ± 488.73 -0.02 ± 371.77 -0.690 0.499 a

arepresents independent samples t-test; brepresents Mann-Whitney U test.