Table 2.
Meta-regression analysis of PMOF in fracture risk assessment in plateau population.
| Parameter | Category | Number of studies | Sensitivity (95% CI) | P1 | Specificity (95% CI) | P2 |
|---|---|---|---|---|---|---|
| PMOF with BMD (MOFT) | Yes | 4 | 0.87 (0.72–1.00) | 0.12 | 0.75 (0.43–1.00) | 0.71 |
| No | 9 | 0.56 (0.35–0.78) | 0 | 0.84 (0.67–1.00) | 0 | |
| Qinghai–Tibetan plateau region (area) | Yes | 5 | 0.62 (0.35–0.89) | 0.42 | 0.96 (0.90–1.00) | 0.01 |
| No | 8 | 0.73 (0.54–0.92) | 0 | 0.61 (0.40–0.82) | 0 | |
| The gold standard is fracture (index test) | Yes | 4 | 0.81 (0.61–1.00) | 0.38 | 0.78 (0.47–1.00) | 0.85 |
| No | 9 | 0.62 (0.40–0.85) | 0 | 0.83 (0.65–1.00) | 0 | |
| Includes all genders (gender) | Yes | 7 | 0.72 (0.52–0.92) | 0.94 | 0.93 (0.84–1.00) | 0.02 |
| No | 6 | 0.68 (0.45–0.91) | 0 | 0.59 (0.26–0.91) | 0 | |
| Cohort study (experimental design) | Yes | 2 | 0.71 (0.33–1.00) | 0 | 0.85 (0.52–1.00) | 0 |
| No | 11 | 0.69 (0.50–0.89) | 0.96 | 0.81 (0.63–0.98) | 0.83 |
PMOF, probability of major osteoporotic fracture; BMD, bone mineral density.