Fig 6.

At 6 months of age, Aβ is localized in the soma of cells forming clusters in the hippocampus of AD11 mice (B) and is absent in control mice (A). At this age, treatment with rhNGF (C) and GAL (D) decreases the number of Aβ-positive clusters of cells. A more prolonged treatment, started at 4 months of age, further decreases the number of clusters in AD11-treated mice (G) compared with control mice (E) and untreated mice (F). (H) Treatment with GAL does not result in a further decrease of the number of Aβ-positive clusters of cells. (Scale bar = 100 μm.)