Table 2.
Characterization of class II bacteriocin biosynthetic gene clusters in Clostridium estertheticum complex genomes.
| Strain | Species | Class | Precursor peptide sequence* |
|---|---|---|---|
| CM038 | Candidatus C. mucoides | IIa | MNTLQENELELLNGGVYYANGVHCDKTHCWVDWGEARGAIGQIVVNGWIQNGPFSHL |
| CF013 | C. estertheticum | IIb |
MELNRNFETLETNELENIDGGSFLLACGIITAGVGVFKLGVEVGKELRSAYDKR MNNLIELNESDLSEINGGIWPWLVAVGAAKATPYVVAGTIFVGGVVVGFVNGKK |
| CS001 | Candidatus C. turicensis | IIb |
MVELSQNELIDVNGGGGDDFSHDLGVFVGRKLHDLYDKAMSNSEERNNNKEYWRYKKGVNG MENINCIELTENELCDVHGGSVLGGIALFGGVVCAINETYKFGKGVVEGWKNN |
| CF009 | C. estertheticum | IId | MRELRIKEQKSICGGTMYQFTDLTTGWLYTDTNFYNLYCTRAAASKLHPTHAYSTITP |
| CM042 | Candidatus C. bubulae | IId | MNKLKMSELEQINGGGPLGGFVVGYLGGKAIDWAVKHPPGKMSPSHKYGQPHGGFL |
| CF003 | C. estertheticum | Unclassified |
MDNTFCELNENELMCINGGGKGDALMTVGGVGVGVGLSCAGEAVTAAFLVSNPIGWGILAGSAAVGAGAYLSSHS MENIFCELNENELMYINGGNPGAALIGVGGTAVTAGLGCAGEAVTAAFLVSNPIGWGILAGSAAVGAGVYYINK MELEYNDGLNELTFTELDEINGGDGGAFALIGAAMAGGWAFTKAAHETPWVFITVM |
*
The leader peptide is in bold letters while the GG cleavage site is written in bold.