Table 2. Comparison of the available clinical characteristics of our study cohort with SEER-EES cohort and the skeletal ES cohort treated at our institute .
| Demographic or clinical characteristic | EES-current cohort N (%) (2021) |
EES-SEER cohort N (%) (1973–2007) |
p value | Skeletal ES- ≤15 years cohort treated at our institute, N (%) (2013) |
p value |
|---|---|---|---|---|---|
| Total number | 106 | 683 | 192 | ||
| Sex | |||||
| Male | 59 (55.7) | 365 (53.4) | 109 (56.8) | ||
| Female | 47 (44.3) | 318 (46.6) | 0.67 | 83 (43.2) | 0.853 |
| Age | |||||
| Median in years (range) | 10 (0.7–15) | 19.5 (0–39) | 11 (0.8–15) | ||
| <10 years | 53 (50.0) | - | 77 (40.1) | ||
| ≥10 years | 53 (50.0) | - | 115 (59.9) | 0.147 | |
| Primary site | |||||
| Axial | 78 (73.9) | 498 (72.9) | 86 (44.8) | ||
| Appendicular | 28 (26.4) | 185 (27.1) | 0.885 | 106 (55.2) | <0.001 |
| Pelvic primary | |||||
| Pelvic | 11 (10.2) | 135 (19.8) | 33 (17.2) | ||
| Non-pelvic | 95 (89.8) | 548 (80.2) | 0.021 | 159 (82.8) | 0.113 |
| Metastases | |||||
| Yes | 27 (25.5) | 206 (30.1) | 40 (20.8) | ||
| No | 79 (74.5) | 477 (69.9) | 0.325 | 152 (79.2) | 0.359 |
| Tumor size | |||||
| ≥10 cm | 31 (28.9) | 278 (40.7) | 0.025 | 86 (44.8) | 0.009 |
| ≥8 cm | 48 (45.3) | - | 124 (64.6) | 0.001 | |
| Local therapy | N = 98 | N = 189 | |||
| Definitive RT | 58 (59.1) | 50.1 | 56 (29.6) | ||
| Surgery + RT | 37 (37.9) | 67 (35.4) | |||
| Surgery only | 3 (3.0) | - | 66 (34.9) | 0.007 | |
| Histological necrosis | N = 31 | N = 121 | |||
| 100% | 5 (16.1) | - | 51 (42.1) | ||
| 90%–99.9% | 9 (29) | 36 (29.8) | |||
| <90% | 17 (54.8) | - | 34 (28.1) | 0.007 |