TABLE 2.

Key odor-active compounds identified in cigar tobacco leaves (SBSE-GC-O-MS).

Odor description	Compound	RT	RI	Odor threshold (μg/L)	Relative content (%)	OAV	VIP	Possible origin
Woody, citrus (lemon, citrus), fresh pine, floral (rose, saffron, violet), grassy, spicy, herbal/Medicinal, sweet, creamy/Fatty	Cyclohexene, 1-methyl-4-(1-methylethenyl)-, (S)-	10.268	1,031	0.034	0.075	0.899	0.578	Terpenoid biosynthesis
	Bicyclo [3.1.1]heptane, 6,6-dimethyl-2-methylene-, (1S)-	11.996	​	4.16	3.435	0.068	1.025	Terpenoid biosynthesis
	D-limonene	12.905	​	0.034	4.396	0.899	1.182	Terpenoid biosynthesis
	Cyclohexanol, 1-methyl-4-(1-methylethenyl)-, acetate	13.077	1,317	ND	3.356	0	1.117	Terpenoid biosynthesis
	Nonanal	15.44	1,104	0.001	0.057	604.732	0.143	Fatty acid oxidation
	Megastigmatrienone	31.508	1,473	ND	1.306	0	0.759	Carotenoid degradation
	3,7,11,15-Tetramethyl-2-hexadecen-1-ol	39.35	2,116	ND	8.022	0	3.152	Chlorophyll/Phytol degradation
	Neophytadiene	38.237	1837	ND	16.910	0	3.799	Chlorophyll/Phytol degradation
Amine-like/Aminic	6-Quinolinamine, 2-methyl-	28.349	​	ND	1.682	0	1.512	Maillard reaction
Smoky	Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-	24.39	1,361	470	42.828	1.086	7.684	Pyrolysis products of alkaloids
Odorless/No distinct odor	1,5,9,11-Tridecatetraene, 12-methyl-, (E, E)-	13.781	​	ND	1.247	0	1.176	Carotenoid degradation
	Pyridine, 3-(3,4-dihydro-2h-pyrrol-5-yl)-	26.747	1,427	ND	1.382	0	0.620	Pyrolysis products of alkaloids
	2,3′-dipyridyl	30.009	1,556	ND	6.058	0	1.948	Pyrolysis products of alkaloids