Table 2.
Sex-stratified comparisons of vitamin B6 biomarkers between participants aged <50 and ≥50 years.
| Variable | Males | Females | ||||
|---|---|---|---|---|---|---|
| <50 years | ≥50 years | p value | <50 years | ≥50 years | p value | |
| PLP (nmol/L) | 38.44 (26.22, 50.54) | 31.68 (23.91, 40.54) | 0.039 | 39.65 (27.43, 56.85) | 41.38 (31.08, 50.17) | 0.185 |
| PL (nmol/L) | 14.66 (11.25, 17.65) | 14.00 (11.01, 16.27) | 0.457 | 14.78 (11.61, 17.95) | 16.99 (14.24, 19.92) | 0.002 |
| PA (nmol/L) | 15.67 (12.94, 18.07) | 17.25 (13.76, 21.35) | 0.080 | 15.23 (11.68, 18.84) | 18.45 (14.14, 22.87) | 0.001 |
| PLP/PL | 3.82 ± 1.13 | 3.39 ± 0.83 | 0.002 | 3.79 ± 0.85 | 3.58 ± 0.83 | 0.097 |
| PLP/PA | 3.27 (2.27, 4.21) | 2.64 (1.87, 3.36) | 0.001 | 3.50 (2.35, 4.49) | 3.25 (2.32, 4.23) | 0.271 |
| PAr | 0.25 (0.19, 0.33) | 0.31 (0.24, 0.39) | 0.002 | 0.25 (0.18, 0.32) | 0.26 (0.19, 0.32) | 0.373 |
Statistical significance was defined as two-tailed p < 0.05, with significant results bold. PAr = PA/(PLP + PL). PLP, pyridoxal 5′-phosphate; PL, pyridoxal; PA, 4-pyridoxic acid.