Table 2.
Sex-stratified comparisons of vitamin B6 biomarkers between participants aged <50 and ≥50 years.
| Variable | Males | Females | ||||
|---|---|---|---|---|---|---|
| <50 years | ≥50 years | p value | <50 years | ≥50 years | p value | |
| PLP (nmol/L) | 38.44 (26.22, 50.54) | 31.68 (23.91, 40.54) | 0.039 | 39.65 (27.43, 56.85) | 41.38 (31.08, 50.17) | 0.185 |
| PL (nmol/L) | 14.66 (11.25, 17.65) | 14.00 (11.01, 16.27) | 0.457 | 14.78 (11.61, 17.95) | 16.99 (14.24, 19.92) | 0.002 |
| PA (nmol/L) | 15.67 (12.94, 18.07) | 17.25 (13.76, 21.35) | 0.080 | 15.23 (11.68, 18.84) | 18.45 (14.14, 22.87) | 0.001 |
| PLP/PL | 2.59 ± 0.76 | 2.29 ± 0.56 | 0.002 | 2.57 ± 0.57 | 2.42 ± 0.56 | 0.097 |
| PLP/PA | 2.33 (1.69, 3.11) | 1.91 (1.40, 2.47) | 0.001 | 2.45 (1.79, 3.30) | 2.30 (1.74, 3.11) | 0.271 |
| PAr | 0.31 (0.24, 0.40) | 0.37 (0.29, 0.46) | 0.002 | 0.30 (0.22, 0.37) | 0.31 (0.24, 0.39) | 0.373 |
Statistical significance was defined as two-tailed p < 0.05, with significant results bold. PAr = PA/(PLP + PL). PLP, pyridoxal 5′-phosphate; PL, pyridoxal; PA, 4-pyridoxic acid.