Table 2.
Genotype and allele distributions of NLRP3, AIM2, and IFI16 polymorphisms in all study groups
| Gene (SNP ID) |
Genotypes and alleles | H N = 80 N (%) |
PB N = 80 N (%) |
PC N = 80 N (%) |
χ2 p value |
Fisher’s exact p value |
|---|---|---|---|---|---|---|
|
NLRP3 (rs4612666) |
CC CT TT |
45 (56.25) 32 (40.00) 3 (3.75) |
36 (45.00) 39 (48.75) 5 (6.25) |
38 (47.50) 33 (41.25) 9 (11.25) |
0.263 | 0.291 |
| HWE | 0.649 | 0.421 | 0.905 | |||
| C | 122 (76.25) | 111 (69.38) | 109 (68.13) | 0.224 | 0.220 | |
| T | 38 (23.75) | 49 (30.62) | 51 (31.87) | |||
|
AIM2 (rs2793845) |
TT GT GG |
61 (76.25) 18 (22.50) 1 (1.25) |
68 (85.00) 11 (13.75) 1 (1.25) |
64 (80.00) 15 (18.75) 1 (1.25) |
0.724 | 0.679 |
| HWE | 1.000 | 0.961 | 1.000 | |||
| T | 140 (87.50) | 147 (91.87) | 143 (89.37) | 0.438 | 0.463 | |
| G | 20 (12.50) | 13 (8.13) | 17 (10.63) | |||
|
IFI16 (rs75985579) |
GG AG AA |
60 (75.00) 20 (25.00) 0 (0) |
63 (78.75) 15 (18.75) 2 (2.50) |
52 (65.00) 28 (35.00) 0 (0) |
0.056 | 0.054 |
| HWE | - | 0.691 | - | |||
| G | 140 (87.50) | 141 (88.12) | 132 (82.50) | 0.282 | 0.302 | |
| A | 20 (12.50) | 19 (11.88) | 28 (17.50) |
HWE Hardy-Weinberg equilibrium, H Healthy, PB Grade B periodontitis, PC Grade C periodontitis
p < 0.05