Table 4.
Association of polymorphisms with advanced attachment loss (CAL ≥ 7 mm) in different genetic models
| Gene (SNP ID) |
Model | Genotypes | Adjusted OR (95% CI) |
p |
|---|---|---|---|---|
|
NLRP3 (rs4612666) |
Codominant |
CC vs. CT CC vs. TT |
1.40 (0.76–2.58) 5.30 (1.29–21.72) |
0.275 0.021 |
| Dominant | CC vs. CT + TT | 1.66 (0.92–2.98) | 0.091 | |
| Recessive | CC + CT vs. TT | 4,59 (1.15-18,39) | 0.031 | |
| Overdominant | CC + TT vs. CT | 1.19 (0.66–2.16) | 0.560 | |
| Additive | CC vs. CT vs. TT | 1.75 (1.08–2.84) | 0.024 | |
|
AIM2 (rs2793845) |
Codominant |
TT vs. GT TT vs. GG |
2.58 (0.17–39.94) 0.75 (0.35–1.62) |
0.499 0.470 |
| Dominant | TT vs. GG + GT | 0.81 (0.39–1.71) | 0.586 | |
| Recessive | TT + GT vs. GG | 2.76 (0.18–42.55) | 0.466 | |
| Overdominant | GG + TT vs. GT | 0.74 (0.35–1.59) | 0.438 | |
| Additive | TT vs. GT vs. GG | 0.90 (0.46–1.77) | 0.764 | |
|
IFI16 (rs75985579) |
Codominant |
GG vs. AG GG vs. AA |
1.65 (0.85–3.21) - |
0.142 0.999 |
| Dominant | GG vs. AA + AG | 1.69 (0.87–3.27) | 0.123 | |
| Recessive | GG + AG vs. AA | - | 0.999 | |
| Overdominant | GG + AA vs. AG | 1.69 (0.87–3.28) | 0.123 | |
| Additive | GG vs. AG vs. AA | 1.70 (0.89–3.26) | 0.111 |
CAL Clinical attachment level, OR Odds ratio, CI Confidence interval
p < 0.05, Statistical differences are marked in bold